Companies

Oncology/Therapeutics

At Healthtech, we are developing precision oncology therapeutics, positioning for significant value creation as the pipeline progresses to clinical development.

Varian Biopharmaceuticals

Targeting aPKCi in Multiple Cancer Types
VarianBio is developing two formulations of its proprietary aPKCi inhibitor. VAR‑101, a topical formulation, can be de-risked through an efficient first‑in‑man proof of concept study in Basal Cell Carcinoma (BCC), which represents a large medical need and a potentially significant commercial opportunity. VAR‑102, an oral systemic formulation, is planning a solid tumor “basket” trial for aPKCi/Gli1/KRAS tumors, with an emphasis on non-small cell lung cancer. VarianBio believes there could be utility for VAR‑102 in acute myeloid leukemia as monotherapy or in combination with ara‑C.

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Advanced Device and Diagnostics

We are developing ultrasound diagnostics and electromagnetic device therapies through our portfolio companies MediScan and RevHeart.

MediScan

MediScan is developing software to enable rapid and accurate triage at the bedside with AI-based analysis of point-of-care ultrasound (POCUS) images of the chest (lung) and musculoskeletal system (tendon). The near-term focus is developing training the AI algorithms with validated images.

RevHeart

RevHeart is discovery stage company focused on novel approaches to correct cardiac rhythm abnormalities using electromagnetic waveforms in an innovative approach called entrainment. Entrainment, which is currently used in tachycardia (rapid heartbeat), works by linking the patient’s abnormal heart rhythm together with a normal heart rhythm, and gently encouraging the abnormal rhythm to revert to a more normal rhythm.

Pipeline

Diagnostics

Company Technology/Disease Proof-of-Concept/ Prototype Validation Regulatory Clearance

MediScan

Computer-Assisted Triage Software /
Lung

Proof-of-Concept/ Prototype Phase in progress
Validation Phase not started
Regulatory Clearance Phase not started

MediScan

Computer-Assisted Triage Software /
Musculoskeletal

Proof-of-Concept/ Prototype Phase in progress
Validation Phase not started
Regulatory Clearance Phase not started

RevHeart

Electromagnetic Device /
Cardiac Rhythm Abnormalities

Proof-of-Concept/ Prototype Phase in progress
Validation Phase not started
Regulatory Clearance Phase not started